Restoring neuronal bioenergetics in tauopathy via mitochondrial transfer
A Webinar by Dr. Amandine Grimm, University of Basel
Tauopathies such as Alzheimer’s disease are characterized by progressive neuronal dysfunction, in part driven by impaired mitochondrial bioenergetics and dynamics.
In this webinar, will start by presenting how abnormal tau impacts mitochondrial function in neurons. Then, she will present recent findings from two complementary studies conducted by her group. The first explores how abnormal tau protein influences intercellular mitochondrial transfer between astrocytes and neurons. The second study investigates the therapeutic potential of mitochondrial transplantation, showing that the exogenous delivery of healthy astrocytic mitochondria enhances bioenergetics and promotes neurite outgrowth in tauopathy neurons.
Together, these findings shed light on the mechanistic link between tau and mitochondrial communication, and open novel avenues for cell-based mitochondrial therapies in neurodegenerative disease.
Event details:
- Date: 18.12.2025
- Time: 16:00
- Duration: 45 minutes (includes Q&A)
- Location: Online (link to be provided upon registration)
- Costs: Free of charge
Register today:
The Dementia Update - Virtual Series is a monthly online event designed to promote knowledge exchange among experts in neurodegenerative disorders. It brings together researchers, clinicians, caregivers and industry professionals to share the latest research, and innovations. Each 45-minute session features a presentation, offering a platform for networking, idea exchange and exploring future collaborations.
Be part of this exciting virtual session and secure your spot!
About the speaker
Dr. Amandine Grimm is featured on our community platform’s expert list. Visit her profile to explore her research interests, ongoing projects, publications, and potential collaboration opportunities.
