Jean-Yves CHATTON
Prof.
Principal investigator
UNIL - University of Lausanne
Department of Fundamental Neurosciences
Expertise and Interests
Primary field of expertise
Basic research
Research interest
Deciphering Astrocyte-Neuron Interactions in Brain Metabolism and Signaling. Astrocytes, positioned between neurons and blood vessels, play a key role in controlling the brain’s extracellular environment and energy metabolism. They detect neuronal activity and respond by releasing lactate, which supplies neurons with energy and modulates their activity. Jean-Yves Chatton and his team study these interactions in genetically modified mice and human brain tissue, using advanced imaging, electrophysiology, and optogenetics. Their research aims to understand how these dynamics affect memory and motor function in both healthy and Alzheimer’s-affected brains.
Research focus
Alzheimer’s disease
Animal models
In vitro models
Pharmacological treatment
Non-Pharmacological treatment
Neuroinflammation
Oxidative stress
Metabolism
