Kevin Richetin

Passionate about photography and microscopy, I discovered my interest in neuroscience through imaging. Observing the intricate structures of living systems under the lens led me to explore the neurobiological basis of behavior using animal models, which naturally steered me toward neuroethology. During my PhD, I studied the mechanisms underlying neurological disorders, but I soon felt the need to get closer to real clinical questions and work on issues with a direct impact on patients. Today, my research aims to bridge fundamental neuroscience and clinical applications, always prioritizing the clinical perspective. I focus particularly on extracellular vesicles (EVs) and their role in pathological brain aging, especially in proteopathies involving tau, α-synuclein, or β-amyloid. My approach integrates omics analyses, advanced microscopy, and in vitro and in vivo models. To translate these findings into clinical practice, I collaborate closely with experts in neuropsychology and brain imaging. My goal is to develop brain surveillance tools capable of detecting early biological alterations linked to pathological aging. By identifying specific EV signatures and combining these data with artificial intelligence and neuroimaging approaches, I aim to better understand the dynamics of proteopathies and pave the way for earlier, more reliable, and personalized diagnostics for neurodegenerative diseases.